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Paediatrics

There are a number of specialist services that support children’s health in Solent NHS Trust and engage in national research to improve clinical outcomes.

On-going Research

Medication adherence in young people taking ADHD medication no 1 This feasibility study aims to on analyse the current methods and tools available to measure young people / children's adherence to medication and development of a mobile application and assessing it's affects on patient adherence.
NEUCHILD V3.0 - A Randomized, Placebo-Controlled Study to Investigate the Efficacy and Safety of Circadin® To Alleviate Sleep Disturbances in Children with Neurodevelopment Disabilities The main purpose of this study is to see if the study medicine (Circadin) can help children with autism spectrum disorders or similar neurogenetic diseases, improve their quality of sleep. Researchers also want to find out if how safe Circadin® is and what the side effects may be.  In addition, this study will compare Circadin® with a placebo to see if taking Circadin® is better than taking a placebo.  The placebo is a mini-tablet that looks like Circadin® but has no active ingredient in it.
Power Up - The Development and Trailing of 'Power Up': A Tool for Young People with Internalising / Emotional Disorders to Make Shared Decisions in Ch The main aims of the project are to understand the beliefs, experiences, and values from young people, their parents/guardians and clinicians in relation to Shared Decision Making in CAMHS. To also use responses from the first objective and focus groups to develop ‘Power Up’ a tool to facilitate Shared Decision Making in CAMHS. ‘Power Up’ will then be used in selected CAMHS sites to establish if patients can be recruited and followed up with measures.
ASD-UK - An Epidemiological ASD Study and Establishing a Research Database v1.0 At present there is no UK database of children with ASD and their families. This research piece aims to construct a UK ASD Research database (ASD-UK) so research teams can recruit families to research studies in the future. For researchers, an  ASD-UK platform and infrastructure will facilitate families’ inclusion in research studies, improving recruitment of children and families to a range of collaborative genetic, phenotypic and intervention studies, and strengthening the UK’s position in the autism research field. For UK families of children with ASD, a research database will improve access to making a contribution to research studies, and to setting the research agenda. Not only will this mean that children and families are more able to participate, but they will have increased early access to new techniques and technologies which may offer benefit.
FADES - Feeding and Autoimmunity in Down's syndrome Evaluation Study This study aims to establish a cohort of children with Down’s Syndrome (DS) in whom they can study the associations between early infant feeding, infections and the development of autoimmunity in DS.  They will document early infant feeding history and medical history over a 5 year period.  By studying their DNA, their gut microbiome and the development of antibodies against their own cells (auto-antibodies) and antibodies to bovine serum albumin they aim to establish whether there is a link between early infant feeding and progression to autoimmune conditions in children with DS.  This would provide information to enable the development of feeding interventions for babies born with DS in the future.
MAAS: Manchester Asthma and Allergy Study: 13-15 year follow-up This is an established birth cohort study investigating the risk factors for the development of asthma and allergy in childhood where the children have already been seen on many occasions.  The study team intend to see these children again for a clinical follow-up between 13 and 15 years of age.